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WHAT’S Fludrex

WHAT’S Fludrex

Fludrex is a pain reliever and decongestant syrup tablet, as Fludrex tablets contain the active ingredients Acetamenophine, Chlorpheniramine, and Pseudoephedrine. The drug is made up of formulae that are considered Anti-histaminic, as it works to remove congestion and relieve pain and treat congestion and pain related to high-pressure sinuses. Fludrex also drains the nose and chest of fluids.

Chlorpheniramine Maleate or Chlorphenamine Maleate is an antihistamine drug and an inhibitor of histamine one receptors in the blood vessels, respiratory system, and digestive system, where the drug binds to the receptors in human cells, thus neutralizing the effect of histamine on these cells. The histamine result causes the sensitivity of the human skin and nose and the appearance of allergic reactions such as itching, rashes, sneezing, tears, and runny nose. Chlorpheniramine is used to treat allergies and these symptoms, as it belongs to the first generation of antihistamines one and passes through the blood-brain barrier, which may cause drowsiness.

Chlorpheniramine is a moderate strength antihistamine and anticholinergic, and weak sedative.

Fludrex Drug Indications

  • It is used in the treatment of symptoms associated with colds and hay fever, and various allergies.
  • It is also used in the treatment of headaches, sinus pain, in addition to nasal and sinus congestion.
  • Allergic Rhinitis.
  • Urticaria.
  • To treat allergic reactions, rash, and itching that occur as a result of an allergy.

Fludrex Drug Contraindications

  • It is forbidden to use it for people suffering from hypersensitivity to one of the medicine components.
  • It should not be used for patients with asthma attacks.
  • It is contraindicated for those suffering from symptoms of an enlarged prostate.
  • It is prevented in cases of deficiency of the enzyme glucose-6-phosphate dehydrogenase.
  • Neonates and premature babies (who were born prematurely).
  • Breastfeeding mother.
  • Sleep apnea.

Fludrex Drug Side Effects

  • Dizziness and drowsiness may occasionally occur, as well as a dry mouth.
  • Sometimes the medicine causes dryness of the nose or throat, as well as headache and nausea.
  • The treatment may cause nervousness, and difficulty breathing may occur.
  • There may be chest tightness, as well as swelling of the face.
  • It may cause chest pain, dark urine, or light-colored stools.
  • Frequent urination may occur, the difficulty of urination, along with hallucinations, rapid heart rate.
  • Stomach pain; due to nervousness.
  • The treatment may cause tremors and unusual tiredness, accompanied by skin yellowing.

Fludrex Drug Precautions

  • When using the medicine, avoid drinking alcohol or using sedatives and hypnotics, which may increase dizziness.
  • The use of the drug leads to a depression in the central nervous capacity. Therefore, activities that require mental attention should be avoided at the beginning of using the medication until it is accustomed to it.
  • The drug should be used with caution in cases of narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, or bladder neck obstruction.
  • Caution should be exercised when using this medicine in the elderly:
  • Consideration should be given to first using antihistamines that do not have a nonanticholinergic antihistamine for treating allergies in the elderly.
  • It is preferable to avoid its use in the elderly due to the high incidence of anticholinergic side effects.
  • The rate of elimination by the body of the drug decreases in the elderly, which increases the incidence of a reduced level of consciousness, dry mouth, constipation, and other anticholinergic symptoms, and the occurrence of drug poisoning.
  • It may exacerbate lower urinary tract diseases or benign prostatic hyperplasia.
  • Patients of diabetes, hypertension, increased thyroid hormones release, epilepsy, liver, and kidney disease.

Fludrex Drug Dosage

Timing: preferably taken in the evening, with or without food.

Adults

Usual adult dose for treatment of Allergic Rhinitis, Urticaria, Allergies, hay fever, and cold symptoms:

  • Tablets and syrup: 4 mg orally every 4: 6 hours.
  • Extended-release: 8: 16 mg by mouth every 9 to 12 hours, or 16 mg by mouth daily.
  • Maximum dose: 32 mg per day.

Usual Adult Dose for Allergic Reaction:

  • Injections: Allergic reaction to blood or plasma transfusion: 10-20 mg by intravenous, intramuscular, or subcutaneous injection as a single dose.
  • Non-exacerbation of allergies: 5: 20 mg, intravenously, intramuscularly, or subcutaneously as a single dose.
  • Maximum parenteral dose: 40 mg per day.
  • Via the mouth: Tablets and syrup: 4 mg orally every 4: 6 hours.
  • Extended-release: 8: 16 mg by mouth every 9 to 12 hours, or 16 mg by mouth daily.
  • Maximum dose: 32 mg per day.

The elderly

  • 4 mg by mouth one to two times daily.
  • Extended-release: 8 mg orally, once in the evening.
  • Consideration should be given to first using antihistamines that do not have a nonanticholinergic antihistamine for treating allergies in the elderly.
  • It is preferable to avoid its use in the elderly due to the high incidence of anticholinergic side effects.
  • The rate of elimination by the body of the drug decreases in the elderly, which increases the incidence of a reduced level of consciousness, dry mouth, constipation, and other anticholinergic symptoms, and the occurrence of drug poisoning.
  • It may exacerbate lower urinary tract diseases or benign prostatic hyperplasia.

Children

  • Safety and efficacy have not yet been established in children under six months of age.

Usual pediatric dose for treatment of Allergic Rhinitis, Urticaria, Allergies, hay fever, and cold symptoms:

  • From age 3: 5 months: Extended-release syrup: 0.5 mg orally every 12 hours.
  • From 6: 8 months: Extended-release syrup: 1 mg orally every 12 hours.
  • From age 9: 18 months: extended-release syrup: 1: 1.5 mg orally every 12 hours.
  • From 18 months of age: 6 years: Extended-release syrup: 2 mg orally every 12 hours.
  • From age 2: 5 years: 1 mg orally every 4 for 6 hours.
  • From the age of 6: 11 years: Tablets and syrup: 2 mg orally every 4 for 6 hours.
  • Extended-release: 4: 8 mg orally every 12 hours, the dose should not exceed 16 mg per day or 8 mg at night before bedtime or during the day.
  • From age 12 years and over: Tablets and syrup: 4 mg orally every 4: 6 hours.
  • Extended-release: 8: 16 mg orally every 8-12 hours, or 16 mg orally once a day.

Renal Dose Adjustments

Elimination time is increased in patients with renal impairment. These patients should be monitored for excessive hypnosis and other side effects resulting from drug combination.

The use of the drug leads to a depression in the central nervous capacity. Therefore, activities that require mental attention should be avoided at the beginning of using the medication until it is accustomed to it.

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